Randolph Avenue is unique in that only one block of it carries traffic in both directions. From its origin at Highland Avenue on the Passaic-Clifton line to a merge with Parker Avenue, it is one-way northbound. From Clifton Avenue to its northern end at Lexington Avenue, it is one-way southbound. The latter section became a one-way road when NJ 21 was completed adjacent to it, and an exit ramp was built allowing direct access onto Randolph Avenue.
| Mile | Street Name | Feature (South to North) |
| 0.00 | CR 627 BEGINS, Clifton City | |
| 0.00 | Randolph Ave | (Highland Ave, CR 626) |
| 0.09 | Randolph Ave | (Lake Ave) [Shopping center entrance] {signal} |
| 0.26 | Randolph Ave | Ackerman Ave {signal} |
| 0.39 | Randolph Ave | (Clifton Ave, CR 611) [Cheever Ave] {signal} |
| 0.86 | Randolph Ave | (Lexington Ave, CR 625) {signal} |
| 0.86 | CR 627 ENDS, Clifton City | |